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Professor Gang Bao presents seminar April 26, 2018

ndavis • Date: April 18, 2018

Prof. Gang Bao

Seminar title: "Nanomedicine and Genome Editing Approaches for Disease Therapies" Abstract excerpt: The integration of biomolecular engineering, nanotechnology and biology is expected to produce major breakthroughs in medical diagnostics and therapeutics. Due to the size-compatibility of nano-scale structures with proteins and nucleic acids, the design, synthesis and application of nanoprobes, nanocarriers and nanomachines provide unprecedented opportunities for achieving a better control of biological processes, and drastic improvements in disease detection, therapy, and prevention.

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Dr. Mehmet Toner to give Edison Lecture Series seminar April 12, 2018

ndavis • Date: April 5, 2018

Prof. Mehmet Toner

Seminar title: "Extreme Microfluidics" Label-Free Sorting of Extremely Rare Circulating Tumor Cells and Clusters Abstract excerpt: Viable tumor-derived circulating tumor cells (CTCs) have been identified in peripheral blood from cancer patients and are not only the origin of intractable metastatic disease but also marker for early cancer. However, the ability to isolate CTCs has proven to be difficult due to the exceedingly low frequency of CTCs in circulation. As a result, their clinical use until recently has been limited to prognosis with limited clinical utility.

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Dr. M. Shane Hutson to give seminar March 29, 2018

ndavis • Date: March 21, 2018

Prof. M.Shane Hutson

Seminar title: "Visualizing Fast Ca2+ Dynamics around Microsurgical Wounds" Abstract excerpt: For epithelial cells to heal a wound, those cells must first become aware of the presence, location, and size of the wound. This knowledge must be shared by cells in direct contact with the wound and those much further away, the latter of which must be recruited by some sort of mechanical or biochemical signal. We have investigated these signaling mechanisms using the exquisite spatial and temporal control afforded by laser-induced microsurgical wounds

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Professor Pablo Iglesias to give seminar March 8, 2018

ndavis • Date: February 27, 2018

Dr. Pablo Iglesias

Seminar title: "Excitable Behaviors, Set Points and Wave Propagation in Migrating Cells" Abstract excerpt: The directed motion of cells in response to chemical gradients requires the coordinated action of three different and separable processes: motility, gradient sensing and polarization. Much effort has been expended understanding each of these processes, and numerous mathematical models have been proposed that explain each one. In this talk I will present a comprehensive model that explains all three aspects of chemotaxis.

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Researchers Tackle Ovarian Cancer Using a Multidisciplinary Approach

nwelding • Date: September 11, 2017

September is National Ovarian Cancer Awareness Month. Ovarian cancer is among the most deadly of all cancers, though because of less awareness, most cities won’t be as blanketed in teal (ovarian cancer’s awareness color) as they are bathed in pink for October’s focus on breast cancer. But researchers at the Harper Cancer Research Institute, a collaboration between the University of Notre Dame and the Indiana University School of Medicine South Bend, are working with community partners to not only foster awareness of ovarian cancer but also to develop tests for early detection, create novel chemotherapies, and target a cure.

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