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Professor Gang Bao presents seminar April 26, 2018

Nancy Davis • DATE: April 18, 2018

Professor Gang Bao presents seminar April 26, 2018

Prof. Gang Bao

The Bioengineering Graduate Program and the Department of Aerospace and Mechanical Engineering, present:

Professor Gang Bao
Foyt Family Professor of Bioengineering
Professor of Chemistry
Department of Bioengineering
Rice University

Seminar Title: "Nanomedicine and Genome Editing Approaches for Disease Therapies"

Date: Thursday, April 26, 2018
Time: 11:30 am to 12:30 pm (Coffee and tea served at 11:10 am)

ABSTRACT:

The integration of biomolecular engineering, nanotechnology and biology is expected to produce major breakthroughs in medical diagnostics and therapeutics.  Due to the size-compatibility of nano-scale structures with proteins and nucleic acids, the design, synthesis and application of nanoprobes, nanocarriers and nanomachines provide unprecedented opportunities for achieving a better control of biological processes, and drastic improvements in disease detection, therapy, and prevention.  Recent advances include the development of multi-functional nanoparticles, nano-structured materials and devices, and engineered nucleases for biological and medical applications.

In this talk I will first present the recent development and application of magnetic nanoparticles in my lab, including heat generation by magnetic iron oxide nanoparticles for hyperthermia and nanowarming, nanoparticle-based stem cell targeting. I will then discuss the design and optimization of CRISPR/Cas9 systems for treating sickle cell disease. The opportunities and challenges in genome editing based treatment of hemoglobinopathies are discussed.